Ruta 40
Argentina's longest road, running more than five thousand kilometres along the Andes from Bolivia to Patagonia.
Updated 18 October 2026

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The RN40 runs the length of Argentina along the eastern side of the Andes, more than five thousand kilometres from the Bolivian border in Jujuy to the far south of Santa Cruz, crossing eleven provinces, dozens of rivers and mountain passes over four thousand metres. It is less a single road than a thread linking wildly different countries: the coloured desert and puna of the northwest, the vineyards of Cuyo, the volcanic south of Mendoza, the lake district of Neuquén and Río Negro, and the empty windswept steppe of Patagonia where settlements can be two hundred kilometres apart. Much of it is now paved, though gravel sections remain, particularly in the far south, and the road has become a journey in itself for drivers and cyclists.
History
Building began in 1935, and the route has changed several times since; until 2004 it was split into Ruta 40 Sur and Ruta 40 Norte, with the zero kilometre marker in the city of Mendoza, at San Martín and Garibaldi streets. On 24 November 2004 the national highway directorate renumbered it and moved the zero marker to Cabo Vírgenes by the Strait of Magellan, though in 2009 there was still no road between the new marker and Punta Loyola, near Río Gallegos, and the plan is to move the northern end to the Bolivian border near Ciénaga de Paicone (Wikipedia, National Route 40 - Argentina).
What's there
- The northwest - puna, coloured rock and high passes in Jujuy and Salta.
- The wine country - vineyards and oasis towns through Cuyo.
- The lake district - the forested Andean corridor in Neuquén and Río Negro.
- The Patagonian steppe - immense empty distances with rare settlements.
When to go
November to March for the Patagonian and high-altitude sections, when passes are open and daylight is long; winter closes parts of the road with snow. The northern sections work year-round, though summer rain can cut them.
Before you go
Distances between fuel, food and lodging are very long in the south, and running on a half tank is a mistake. Gravel sections damage tyres and windscreens, and the Patagonian wind is a constant, tiring force. Doing the whole road takes weeks, and most travellers drive a section rather than the length.
Nearby
The road links Cafayate, Mendoza, Bariloche, El Chaltén and El Calafate among many others.
Key facts
Source: Wikidata, item Q1664702, read on 18 October 2026.
What to pack for Ruta 40
Chosen from what this place is for. Tap a kit for the full checklist.
- Padded shorts - The one thing that makes a full day in the saddle bearable. Find on Amazon
- Warm base layers - Merino or synthetic against the skin - never cotton, which chills when damp. Find on Amazon
- Loose, light, long clothing - Covering up beats bare skin in the desert - and locals dress this way for a reason. Find on Amazon
- Layers for big temperature swings - Warm sun by day, near-freezing at night, even near the equator. Find on Amazon
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Opening times, ticket prices and seasonal closures change - check the official source before you go: official site.


